Spine Service, Sydney Australia
Dr Philip Boughtonn
Dr Philip Boughtonn

Dr Philip Boughtonn

BE (Hons) UNSW, PhD (Eng) USYD

Executive Summary: Industry-Linked Biomed Engineering Leadership

Aim

To lead and support industry-uni linked biomedical engineering R&D and teach/train in this area.

Current Rules

  1. Research Sup. Engineer UNSW
  2. Infrastructure Manager UNSW
  3. Mech Lab Manager UNSW
  4. Honorary Lecturer AMME USYD
  5. Conjoint Lecturer, StGeorge H.
  6. Tech. Director, Spine Service
  7. CI NHMRC Project (Pending)

Interests: Biomimetics, Tissue Eng., Theology

Key Success:

R&D Manager Leading Australia's 1st Spine Implant Development to ISO Compliance and Clinical Trial Stage locally and overseas

Chief Inventor:

BioFI Implant, GRG Fixation, FGM Routes, Resorbable Device

Research Areas:

Medical Devices, Biomaterials, Spine, Biomechanics, Orthopaedics, Tissue Engineering, Bioreactors, Control Systems, FEA, Diagnostics, Sterilization, Equipment design/repair.

Publications:

5 medical device patents, 13 original research papers

Industry Exp:

  • 16 yrs - industry-linked engineering consulting
  • 11 yrs - industry-linked medical device development
  • 4 yrs - medical device manufacturing

Teaching:

10 yrs tutoring, demonstrating, training, lecturing, presenting

Supervision:

5 PhDs, 2 ME, 53 BE Hon, 1 Med ILP, 34 Eng Interns

Management:

4 yrs Com, 10 yrs Lab, 4 yrs Facilities, 4 yrs Project Management,

Profile Raising:

10 yrs event coordination, 9 yrs open day organization

Education & Training: Academic, Quality Systems, Safety Systems

Year Academics
2010 Breathing apparatus training, Drager
2010 Chief Warden Training, UNSW
2009 UNSW NHMRC Grant Writing Course
2009 Fire Safety, Chubb
2008 ISO 13485 MEDICAL DEVICE MANUFACTURING SYSTEMS TRAINING - SeerPharma
2007-2008 StGeorge Spine Service, StGeorge Hospital, Research Seminars
2000-2005 "A Functionally Graded Spinal Disk Prosthesis"
PhD (APAI Industry Scholarship Award) Biomedical Engineering, AMME, The University of Sydney
PhD Thesis accepted on first examination.
Unanimous examiner commendations for novelty, scope and substantial contribution to field
2003 KCPC/CSIRO Polymer Summer School
2002 Institute for Teaching & Learning Effective Tutoring Workshop, The University of Sydney
1995-1999 Bachelor of Engineering Honours, The University of New South Wales
1994 Preliminary Theology Certificate, Moore College
1989-1994 St Andrews Cathedral School, Sydney

Engineering Research Experience: Design, Development, Commercial

RESEARCH SUP. ENGINEER | MECHANICAL LAB MANAGER

UNSW, MSE

  • Management of mechanical / nano-mechanical / tribology / Piezomechanics / Metallic Glass Labs
  • Implimentation of operating, training, safety procedures
  • Development of standard and advanced test methods for composite and homogenous materials
  • Test method design for product samples, medical implants and explants
  • Maintenance, troubleshooting and repair of a range of test equipment and infrastructure facilities

HONORARY LECTURER | BIOMEDICAL ENGINEERING

USYD

  • Chief Investigator for Medical Device Development / RPAH linked Tissue Engineering Research (Current: 12 USYD Honours, 3 USYD PhDs, 1 UNSW Phd, 1 UNSW Masters, Coursework Guest Tutor)

CONJOINT LECTURER IN SPINAL BIOMECHANICS

StGeorge Hospital Biomech Testing/FEA/Diagnostics/Sterilization/Seminars/Tissue Eng/Supervision (Current: 1 BE, 1 ME, 1 PhD)

RESEARCH & DEVELOPMENT / CLINICAL MANAGER

Columna Pty Ltd

  • Key contributor toward spinal implant development and successful ISO13485 accreditation by BSI, 2008
  • Device & instrumentation sterilization design, production environment management, validation testing, ISO documentation, packaging project manager, cadaver trial assistance, design and articulation of new IP, implant biomechanics verification, FEA, materials selection, manufacturing verif./valid.
  • Regulatory requirements, development of SOPs and protocols, clinical research planning, tendering, consultation, trial site liaison, site cleaning and hospital re-sterilization requirements, clinical trial planning.

PRIMARY INVENTOR FOR INDUSTRY-LINKED TECHNOLOGY (Patented)

Bioabsorbables

Novel bioabsorbable orthopaedic fixation device (WO/2008/092192). ASDM Pty Ltd

BioFI Spinal Disk

Bioactive functionally graded intervertebral disk prosthesis (WO/2008/092192). ASDM Pty Ltd

INVENTORSHIP SUPPORT (>20% Contribution, Patented)

Tissue Scaffold

A novel soft tissue conductive scaffold (AU/2009/905343, AU/2009/903433). Biometic Pty Ltd

CDD Implant

Minimally Invasive Spine Tissue Prosthesis, Methods & Instrumentation (WO/2008/064400). Columna Pty Ltd

Diagnostics

Diagnostic System for Back Pain (WO/2008/064398). Orthonova Pty Ltd

COLLABORATORS & CLIENTS (2005-Current)

  • ISO Manufacturing Recommendations, Maverick Biosciences Pty Ltd
  • Vascular Device Design & Development, Endoluminal Sciences Pty Ltd
  • Explant Testing, Materials Characterization, Cochlear Pty Ltd
  • Sterilization Design & Cleanroom Manufacturing, Adventus Pty Ltd/Eye Research Institute UNSW
  • Design & Development, Cellixe Pty Ltd
  • Sterilization Design, Synthes Spine - Early Degen Division
  • Tissue Engineering Design & Operations, Biometic Pty Ltd
  • Device Verification & Validation, Endoluminal Sciences Pty Ltd
  • Design & Development, Orthonova Pty Ltd
  • Device Validation, Allvascular Pty Ltd
  • Cleaning validation, Portland Orthopaedic Pty Ltd
  • Validation testing, Ventracor Pty Ltd
  • Device Development & Knee Wear Test Setup, ASDM Pty Ltd
  • Diabetic Wound Model Mechanical Characterization, Royal Prince Alfred Hospital
  • Spinal Implant Testing, Synthetic Annulus Design & Fabrication, Columna Pty Ltd
  • Tropoelastin Protein Characterization - Elastagen Pty Ltd

Equipment Expertise: Biomechanics, Mechanical, Analytical, Processing

Biomechanics-Quasistatic/Dynamic:

  • BOSE 6-axis EM-SP (5kN/30Nm-AT)
  • BOSE ELF3400 Axial-Torsion EM(5kN/30Nm/up to 100Hz)
  • Instron 8874 Axial-Torsion Servo-H (25kN/50Nm/up to 30Hz)

Microscopy & Micro-Analytical:

  • Leica DM-RXE Optical Microscope
  • Atomic Force Microscope, Dimension 3000, Digital Instruments
  • Jeol, Philips SEMs
  • Mitotuyo Profilometer
  • XRD Siemens D5000

Thermo-Analytical:

  • TA Instruments DMA, DSC

Mechanical, Nanomechanical, Rheological:

  • Hysitron Nanotribometer / AFM / UMIS Ultra Microindentor / United Instrumented Indentor
  • MTS 810 Axial Servo-H (100kN up to 30Hz), Instron 1122, 1185, 1195, 5567 Universal Screw Machines
  • CSM High Temperature Tribometer / CSM Scratch Tester
  • Drop-weight impact testers, Zwick and SATEC Charpy Impact Testing Machines (4J to 300J)
  • Shimadzu Microhardness Testers with Various Indenters
  • Brookfield Rheometer, Strain & Stress Control Rheometers

Process/Production

  • Polymers & Composites: BOY Injection Moulding, Transfer moudling, Vacuum Hot Press
  • Ceramics, Glasses: Hot Press, High Temp Ovens, Glass Forming
  • Metals: Rolling press, machining, design for CNC

Research & Teaching Experience: Academic, Clinical, Industry, Community

  • NHMRC CI3 Applicant & Project Coordinator, Scaffolds to Accelerate Healing in Chronic Wounds, APP1010120, S McLennan (RPAH), N Coleman (USYD), P Boughton (USYD), M Ferry (UNSW), 2010
  • Sustainability Design Workshop, Program Coordinator & Presenter, Faculty Schools Prog., UNSW, 2010
  • Invited Lectures (2), Polymers in Medical Devices, Delegation Program SMSE Series, UNSW, 2010.
  • Invited Lecture, Sterilization & Regulatory Requirements, USYD Biomedical Engineering Program, 2010
  • Invited Lecture, Tissue Engineering Regulatory Issues, USYD Biomedical Engineering, 2010
  • Program Welcome, Materials & Nanotechnology Science Faculty Course, UNSW, 2010
  • Faculty Guest Talk, Sydney University Evangelical Union, 2009
  • Guest Talk, Cochlear Pty Ltd, 2009
  • StGeorge Hospital Spine Service Seminar, St George Hospital, 2009
  • Guest Speaker, Sydney University Association of Biomedical Engineers Seminar, 2009
  • Orthopaedic Engineering Lectures (6), Biomed. Eng. Program, 2007, 2008, 2009
  • Guest Lecture, Principles of Tissue Engineering, Biomed. Eng. Program, 2007
  • Invited Lecture, Veterinary Science, Bioabsorbable Devices and Arthroplasty, Sydney University, 2007
  • Invited Lecture, The Biennial Health Research Conference 5 on Tissue Engineering, USYD, 2006

Awards:

2010 Supervisor of Student Prize for Innovation, Sydnovate, USYD
2009/2010 Supervisor of Postgraduate Prize for Sydnovate Innovation & Engineering Faculty Poster Competition USYD
2009/2010 Supervisor of Postgraduate Equal 1st Prize Winner for UNSW Materials School Poster Competition
2008 UNSW Science Alumni Award
2007 Australasian Society for Biomaterials & Tissue Engineering - 1st place for New Logo Design
2005 Equal 1st Place, AusBiotech/ABSA NSW Student Excellence Awards
2003 UNSW Materials Science Graduate Award
2002 APAI Industry Linkage Award Scholarship (A Functionally Graded Spinal Disk Prosthesis)
2000 Postgraduate Research Scholarship in Fibre-Polymer Composite Biomaterials
2000 1st Prize for Presentations (ACUN-2 Composites in the Transportation Industry, Sydney, 2000)

Research Presentations:

  • Australasian Society for Biomaterials 17th Annual Conference 2007
  • Ausbiotech ABSA Student Excellence Competition, 2005
  • Engineering & Physical Sciences in Medicine 29th Annual Conference 2005
  • European Society for Biomaterials 16th Annual Conference 2001
  • ACUN-3 International Composites Conference 2001
  • The American Ceramic Society International Conference on Adv. Cer. & Composites 2001
  • ACUN-2 International Composites Conference 2000

Original Research Publications (>20% contribution to all publications listed):

Patents:

  • E Boughton, A biocompatible pin, a method of treating joint articular cartilage defects in a bone and a method of accessing a joint surface..., Australian Provisional Patent 2009905343, 2009

  • E Boughton, Porous bioabsorbable composite scaffold, bioabsorbable pump, tissue repair system, method of manufacture a porous bioabsorbable composite scaffold..., Australian Provisional Patent, AU/2009/903433, 2009

  • J Choi, Z Milijasevic, A Diwan , Tissue Prosthesis Insertion System & Method International Patent Publication WO/2008/064400, 2008

  • A Diwan,Diagnostic System, International Patent Publication, WO/2008/064398, 2008

  • P Boughton (Primary Inventor), A Ruys, G Roger, An Intervertebral Disk Prosthesis, International Patent Publication WO2008/092192, 2008. (also contains IP for a bioabsorbable fix. pin)

  • P Boughton (Primary Inventor), A Ruys, G Roger, Bioactive functionally-graded intervertebral disk prosthesis and novel methods of fabrication, detailed within Australian provisional patent 2007900411, 2007

Journal Papers:

  • P Boughton, J Merhebi, C Kim, G Roger, A Diwan, E Clarke, N Amanat, R Ho, A Ruys, An Interlocking Ligamentous Spinal Disk Arthroplasty with Neural Network Infrastructure, Journal of Biomimetics, Biomaterials & Tissue Engineering, 2010.

  • D Strange, S Fisher, P Boughton, T Kishen, A Diwan, Restoration of compressive loading properties of degenerate discs with a nucleus implant - A FEA Study, The Spine Journal, 2010

  • D Chandra Nath, S Bandyopadhyay, P Boughton, Aibing Yu, D Blackburn, C White, Chemically modified fly ash for fabricating super-strong biodegradable poly(vinyl alcohol) composite films, J Materials Science, 2010

  • S Thomson, S McLennan, A Hennessy, P. Boughton, J Bonner, H Zoellner, D Yue, S Twigg, A novel primate model of delayed wound healing in diabetes: dysregulation of connective tissue growth factor, Diabetologia, 2009

  • A Baume, N Coleman, P Boughton, Methods for Achieving Soft Tissue Scaffold Sterility, J Biomimetics, Biomaterials & Tissue Engineering, 2009

  • D Nath, S Bandyopadhyay, P Boughton, A Yu, D Blackburn, C White, High-Strength Biodgradable Poly(vinyl alcohol)/Fly Ash Composite Films, J App Science, 2009

  • D Nath, S Bandyopadhyay, P Boughton, A Yu, D Blackburn, C White, Chemically Modified Fly Ash for Fabricating Super- Strong Biodgradable Poly(vinyl-alcohol) Composite Films, J Materials Science, 2009

  • P Lok, P Boughton, T Kishen, A Diwan, Geometrical & Interfacial Modulation of a Biomimetic Spinal Implant, J Biomimetics, Biomaterials & Tissue Engineering, 2009

  • S Liyanage, P Boughton, G Roger, J Hyvarinen, A Ruys, Design Review & Preliminary Testing For A Biomimetic Absorbable Ligament Anchor, J Biomimetics, Biomaterials & Tissue Engineering, 2009

  • C Wu, Y Ramaswamy; P Boughton; H Zreiqat, Improvement of mechanical and biological properties of porous CaSiO3 scaffolds by poly(D,L-lactic acid) modification, Acta biomaterialia 2008;4(2):343-53.

  • P Boughton, A Ruys A, G Roger, R Rohanizadeh, L Kolos, Functionally graded material for a spinal disk prosthesis. Australasian Physical and Engineering Sciences in Medicine 29(1):107, 2006

  • P Boughton, C Gregory, H Sinclair, S Patrick, M Hoffman, S Bandyopadhyay, Recent Developments in Water-Based Coatings for the Transport Indust ry, in Surface Coatings Aust ralia, 37(9), pp20-25, 2000.

Published Proceeds:

  • P Boughton, A Ruys, Fibre-Polymer Functionally Graded Material, Eur Soc Biomaterials 16th Conf , London, Sep 2001

  • P Boughton, D Ferris, A Ruys, A Ceramic-Polymer Functionally Graded Materials: A Material with Potential as a Spinal Disk Prosthesis, Proc ACUN-3 International Composites Conference, UNSW, Sydney, Feb 2001.

  • P Boughton, D Ferris, A Ruys, A Ceramic-Polymer Functionally Graded Material: A Novel Disk Prosthesis, Proc. 25th Int. Conference on Advanced Ceramics & Composites, Cocoa Beach, Florida, American Ceramic Society, Jan 2001

Employment History:

2010 (Current) ISO13485 Consulting, Maverick Biosciences Pty Ltd
2009 (Current) Operations Consultant, Biometic Pty Ltd
2009 (Current) Consultant, Endoluminal Sciences Pty Ltd
2008 (Current) Research Support Engineer | Lab Manager, MSE UNSW
2009 Technical Director , Testlab Spine Service, St George Hospital Campus
2009 ISO13485 Production Consultant - Institute for Eye Research Ltd
2006-2008 Columna Pty Ltd - R&D Manager/Clinical Manager / St George Spine-Service - Conjoint Lecturer
2006-2007 The University of Sydney / Advanced Surgical Design and Manufacture Pty Ltd Postdoc Res. Assoc. - Bioabsorbable Orthopaedic Technology / Spinal Disk Implant Research
2005 Spine-Med Pty Ltd Synthetic Annulus Design, Manufacturing and Testing
2005-2006 AMME2302 Polymer Materials Lecturer, AMME School, USYD
2001-2007 BOSE ELF 3400 Biaxial Tester - Chief Technician and Training
2000-2004 MECH2300 - Tutoring, Lab Demonstrating, Exam Marking
2003-2007 Biomedical Engineering Website Design & Open Day Coordinator

Referees:

Prof Mark Hoffman Associate Dean (Research) Science | Mechanics, Piezoscience, Biological Materials, Biomaterials
School of Materials Engineering, The University of New South Wales
(W) +61 2 9385 4432; (E) mark.hoffman@unsw.edu.au
A/Prof Ashish Diwan Spine Chief & Director of Eductation-Orthopaedic Surgery-StGeorge
Department of Orthopaedic Surgery, St George Hospital Campus, The University of New South Wales
(W) +612 9588 9622; (E) a.diwan@spine-service.org
A/Prof Andrew Ruys Head of Biomedical Engineering Program , School of AMME Engineering, The University of Sydney
(W) +612 9351 8610; (E) a.ruys@usyd.edu.au
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